Description
Ace-031 Peptide Vial 1mg
ACE-031 Netherlands is a synthesized protein composed of immunoglobulin G1-Fc (known as IgG1-Fc) and activin receptor type IIB (ACVR2B). It binds to myostatin and similar proteins in the muscle, preventing them from functioning normally. However, according to Netherlands research, ACE 031 effectively maintains muscle strength and muscle mass in patients with disorders that result in muscle loss and neuromuscular diseases.
Specifications
Sequence: not available
Size: 1mg | 1mg vial kit
Research
Muscle Growth
When administered intravenously, ACE 031, the IIB activin receptor (ACVR2B) is an effective modulator of muscle growth in humans. ACVR2B binds to and inactivates the muscle growth inhibitor myostatin. According to Netherlands research, taking down the activin receptor increases muscle cell mass in mouse models. The relationship between ace-031 and the therapy of muscle-wasting illnesses like Duchenne Muscular Dystrophy has led to multiple clinical trials (DMD) [1]. Other gametocyte organelles rely on Activin receptors as well, such as sperm. Prostate cancer generally has an inactive receptor, while several kinds of colorectal cancer have damaged or defective receptors.
Ace-031, the anti-catabolic hormone myostatin, plays a critical role in the growth and repair of skeletal muscle, especially in those muscles that are used for exercise. The pituitary gland is the primary source of the hormone, which causes muscle tissue to degenerate and lose density. In low concentrations and low quantities, the hormone is more effective.
In a recent clinical trial results showed that because liposuction and other surgical procedures alter the pituitary gland’s ability to secrete the hormone, those who have undergone these procedures have seen a significant decrease in their hormone production. As a result, myostatin levels drop, and with them, the body’s ability to carry out its normal functions as a whole.
These people have lower levels of the hormone in their blood, and it has been shown that they are unable to gain as much muscle mass as normal people [2]. In addition, the majority of these patients with decreased levels of myostatin become less muscular than the subjects who do not undergo surgery. Netherlands Clinical trials have shown that Ace-031 could counteract these side effects.
The lack of protein in the body after a workout can also have an impact on the production of myostatin. This is referred to as “muscle wasting syndrome” by the scientific community. The amino acid L-Glutamine, which is found in protein supplements, has been shown in one study to increase metabolism and myostatin production [3].
Summary
Ace-031 has many potential applications including as a potential peptide therapy in Duchenne muscular dystrophy and other neuromuscular illnesses where it has reduce muscle loss in patients with minimal side effects. Netherlands Scientific research has found that ACE-031 can significantly aid in building and keeping lean body mass. Furthermore, Netherlands research shows it has powerful anabolic and anti-catabolic properties that maintain maintaining muscle development, and reduce fat deposition.
References:
[1] https://www.clinicaltrials.gov/ ct2/show/NCT01099761
[2] https://onlinelibrary.wiley.com/ doi/abs/10.1002/mus.23539
[3] https://journals.physiology.org/ doi/pdf/10.1152/physiolgenomics. 00223.2010
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