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AICAR Pre-Mixed Pen 50mg Netherlands

AICAR (5-aminoimidazole-4-carboxamide-1–D-ribofuranoside) is a peptide found in the body that stimulates AMP-activated protein kinase (AMPK). It’s frequently utilised as a pharmacological modulator to boost AMPK activity. According to research, AICAR may improve glucose tolerance, lipid profiles, and general metabolic performance.

Pen Kit & Pre-Mixed Cartridge contains:

1 x Pre-Mixed Cartridge (The cartridge is pre mixed with the peptide vial of your choice and Bacteriostatic Water)
1 x Peptide Cartridge Pen
3 x Pen Needle Tips
1 x Pen Carry Case

Please note: Single 1, 2 & 3 Pre-mixed Cartridges do not come with a Pen Kit.

Save 10% when buying 3 cartridges.

£30.19£81.51

SKU PLG: AICA Pen Categories ,

Description

AICAR Pre-Mixed Pen 50mg Netherlands

AICAR pre-mixed pen peptide Netherlands (also known as AICA Ribonucleotide) is the analogue of adenosine monophosphate. It has been used to treat myocardial ischemia following a heart attack. Furthermore, AICA ribonucleotide is an antioxidant that may aid in the prevention of ageing. AICAR Pre-Mixed Pen 50mg is being researched for diabetes, auto-immune disorders, and other inflammatory conditions.


Specifications

Molecular Formula: C9H15N4O8P
Molecular Weight: 338.21 g/mol
Sequence: 5-amino-4-imidazole carboxamide ribotide
aminoimidazole carboxamide ribonucleotide

Size: 1 Single mixed cartridge | 2 Pre mixed cartridges | 3 Pre mixed cartridges | Pen kit with 1 pre mixed cartridge


Research

Muscle growth

Muscle fibres are the fundamental skeletal muscle unit. Muscle fibre types in animals have an impact on meat quality. As a result, AMPK protein activity was assessed in gastrocnemius (GS) muscle fibre composition, enzyme activity, and mRNA expression of muscle fibre type-related genes [1].

AICAR, among other things, increases muscular mass in the body. It is necessary for both muscle growth and muscular mass preservation. It has also been shown in studies to reduce muscle loss.

According to Netherlands research, AICAR pre-mixed pen peptide could one day be used to treat muscle wasting diseases. Furthermore, strenuous exercise improves AICAR’s muscle growth outcomes.

Anti-inflammatory properties

According to recent Netherlands research, AICAR is involved in cellular inflammation. AICAR is related to metformin, a long-used diabetes therapy that is effective in part because of its anti-inflammatory properties.

Asthma, hepatitis, colitis, and atherosclerosis are all protected against by the AICAR pre-mixed pen. In mouse experiments, AICAR pre mixed peptide was proven to lessen inflammation in colitis [2].

AICAR may potentially aid in the treatment of autoimmune illnesses and other inflammatory diseases.

Fertility

AICAR, an AMPK activator, has been found in research on goats, cats, and chickens, among other species, to increase sperm motility, fertilising capacity, and metabolism. [3] [4].

Heart disease

Inflammation is a major contributor to cardiovascular disease (CVD). Netherlands Animal studies have shown that AICAR’s anti-inflammatory properties are so potent that it can help halt the onset of vascular diseases [5].

The researchers intended to explore what would happen if they administered a pre-mixed AICAR pen to atherosclerotic mouse models and monitored the consequences [6]. AICAR decreased the formation of vascular smooth muscle, resulting in a reduction in both short- and long-term difficulties related with stent implantation and placement, according to the findings.

According to the study’s findings, activating AICA ribonucleotide appears to decrease immune responses associated with atherosclerosis. Furthermore, bad cholesterol (LDL) accumulates in the bloodstream, triggering macrophage proliferation and, eventually, a heart attack. AICAR use can help prevent the spread of heart disease and heart attacks, as well as potentially lessen their incidence.

Insulin sensitivity

Extensive Netherlands research on mice reveals that pre-mixed AICAR pen dosages, both high and low, reduce inflammation in adipose tissue, which stores energy as fat [7].

Insulin resistance is connected to inflammation in adipose tissue. Reduced inflammation leads to improved glucose control. AICA ribonucleotide, for example, controls inflammation in adipose tissue via SIRT1 and macrophages.

Obese monkeys lost weight and had better insulin resistance.

According to AICA ribonucleotide studies, both healthy and diabetic mice have reduced inflammatory responses. AICAR pre mixed peptide has been shown to improve insulin sensitivity and minimise inflammatory symptoms.

Summary

AICA ribonucleotide is a protein that modulates insulin receptors and enhances insulin sensitivity in muscle cells and is required for metabolic pathways and energy balance. AICAR peptide hormone has been shown in studies to fight cancer and protect the heart. It also prevents premature blood clotting. As a result, scientists wish to continue investigating this protein. Historically, doctors used AICAR pre-mixed peptide to maintain the blood flowing to the heart. However, the peptide AICA ribonucleotide has the potential to be used as a diabetes treatment due to its capacity to increase tissue metabolism. It accomplishes this by modifying the muscular composition of the body.

References

[1] https://www.tandfonline.com/doi/ full/10.1080/09712119.2021. 1889563

[2] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC4398665/

[3] https://pubmed.ncbi.nlm.nih.gov/ 31079268/

[4] https://www.frontiersin.org/ articles/10.3389/fcell.2017.00025/ full

[5] https://www.frontiersin.org/ articles/10.3389/fphar.2021.7384 20/full

[6] https://www.sciencedirect.com/ science/article/pii/S002228281 3002277

[7] https://www.ncbi.nlm.nih.gov/pmc/ articles/PMC2692788/

Buy AICAR Pre-Mixed Pen 50mg

Pharma Lab Global Netherlands is one of the best locations to purchase high purity AICAR pre-mixed pen peptide for research. Pharma Lab Global is a trusted supplier of peptides worldwide. You have the option to buy AICA Ribonucleotide Nasal Spray and buy AICAR Peptide from here. Buy from Pharma Lab Global Netherlands today!


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DISCLAIMER: All products sold by Pharma Lab Global are for research and laboratory use only. These products are not designed for use or consumption by humans or animals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such. By purchasing from our Website the buyer accepts and acknowledges the risks involved with handling of these products. All articles and product information provided on this Website are for informational and educational purposes only. Handling and use of these products should be restricted to suitably qualified professionals.

Additional information

Cartridge

1 Single mixed cartridge, 2 Pre mixed cartridges, 3 Pre mixed cartridges, Pen kit with 1 pre mixed cartridge

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