Description
B7-33 Peptide Vial
B7-33 pre-mixed pen peptide possesses potent anti-fibrotic properties, especially for acute and chronic diseases such as heart failure, lung inflammation, kidney disease, fibrosis reduction.
B7-33 peptide is a synthetically formed peptide analogous to the B-chain of relaxin-2. It selectively activates the relaxin family peptide receptor 1 (RXFP1) and has demonstrated promising results in providing acute cardio protection and limiting adverse remodelling in rodent subjects with myocardial infarction-related injury.
In animal models of hypertension, B7-33 has been found to reduce blood pressure by activating RXFP1, leading to vasodilation and potentially acting as a therapeutic option in the management of hypertension. In addition, the B7-33 peptide has demonstrated it’s efficacy in reducing myocardial stiffness and airway reactivity, making it a potential treatment for conditions such as myocardial fibrosis and respiratory diseases.
The manufacture of B7-33 as a single-chain peptide is relatively easier and cost-effective compared to similar peptides, making it an excellent candidate for further modification and development. In depth research has shown that B7 33 reduces fibrosis and prolongs survival after injury. Furthermore, it has been shown to reduce excessive scarring after cardiac injury in several Netherlands clinical studies. Some vascular disorders and preeclampsia of pregnancy have also demonstrated promising results.
Specifications
Sequence: VIKLSGRELVRAQIAISG MSTWSKRSL
Physical Appearance:Â White Lyophilised Solid
Form:Â Sterile Filtered White Lyophilized
Solubility:Â Water Soluble
Size: 2mg | 6mg
B7-33 Peptide Vial Benefits
Peptide B7 33 is an anti-fibrotic agent. Reducing fibrosis is a significant focus of research and investigation for acute and chronic diseases like heart failure, lung inflammation, and more. According to Netherlands animal studies, by cutting fibrosis by half in animals, B7-33 could be the first new treatment for heart failure [1].
Using B7-33 to reduce foreign body response to implanted medical devices is also considered an additional use. Because it reduces the growth of fibrotic capsules around implanted devices by half, B7 33 opens up possibilities for new and better implantable medical devices in addition to expanding current ones’ usefulness [2].
Although it is an anti-fibrotic peptide, B7-33 is much more than that. In addition, it has several other properties, including its ability to lower blood pressure and protect the cardiovascular system. There is also evidence from studies in preeclampsia animal models that B7 33 could be an effective treatment for this challenging disease, allowing more women to carry their children to term in a safe manner for both mother and child [3].
Summary
There are many potential benefits to this peptide in human medicine, including having anti-fibrotic effects, the ability to prevent damage to blood vessels. It has proven to be beneficial in the management of preeclampsia and proves as a valuable tool for foreign objects being inserted into the human body.
References
[1] https://pubmed.ncbi.nlm.nih. gov/32295457/
[2] https://pubmed.ncbi.nlm.nih. gov/31713411/
[3] https://www.ahajournals.org/ doi/10.1161/hyp.74.suppl_1. P3042
Buy B7-33 Peptide Vial
Pharma Lab Global Netherlands is one of the best locations to purchase high purity B7 33 peptide vial for research use. Pharma Lab Global is a trusted supplier of peptides worldwide. You also have the option to buy B7-33 nasal peptide spray and buy B7-33 Pre Mixed peptide. Buy from B7-33 Peptide Pharma Lab Global today!
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